Roblox Defenders Depot is an online game where gamers can set up their own base and defend it from incoming enemies. You can team up with your friends to kill all the enemies. Make sure that you’re always ready when a horde of enemies comes across your land and counter them using different weapons.
In the following list, the weapons in Roblox Defenders Depot are categorized into different tiers. The most powerful weapons in tier SS are Satellite and Evil Eye while Force of Nature and Crossbow rank in the S tier. Some weapons in tier A are Accelerator and Crystal Enhancer. Absolute Zero ranks in the B tier and Obelisk ranks in the C tier. The turret is the best weapon in tier D and Black Hole is the most powerful one in E tier. 1M Stature ranks in the F tier.
SS Tier

| Weapons | Tier |
| Satellite | SS |
| Evil Eye | SS |
| Fluxium | SS |
S Tier

| Weapons | Tier |
| Force of Nature | S |
| Crossbow | S |
| Flame Thrower | S |
| Sentry | S |
| Cannon | S |
A Tier

| Weapons | Tier |
| Accelerator | A |
| Crystal Enhancer | A |
| Guardian | A |
| Minigun | A |
| Volcano | A |
| Cataclysm | A |
| Dark Terra | A |
| Retribution | A |
B Tier

| Weapons | Tier |
| Absolute Zero | B |
| Destroyer | B |
| Solar Flare | B |
| Orb of Light | B |
| Orb of Darkness | B |
| Acid | B |
| Wrecking Ball | B |
C Tier

| Weapons | Tier |
| Obelisk | C |
| Overseer | C |
| Particle Eradicator | C |
| Inferno | C |
| Rocket | C |
| Icicles | C |
| Meteor | C |
D Tier

| Weapons | Tier |
| Turret | D |
| Tesla | D |
| Laser Blaster | D |
| Super Soaker | D |
| Equalizer | D |
| Laser | D |
| Spikes | D |
| Ion Field | D |
E Tier

| Weapons | Tier |
| Black Hole | E |
| Plasma Turret | E |
| Saws | E |
| Sun Lasers | E |
| Photon Beam | E |
| Chaos Cannon | E |
F Tier

| Weapons | Tier |
| 1M Stature | F |
| Boom Box | F |
| Wall | F |