This guide uses the knockdown shot weapon technique.
You have to tag the glow blast canister, so you are not confused where to shoot when you knock him down.
The boss needs to be shot three times with the knockdown shot to enter the knockdown status.
You will have the first two right away.
Once recharged, you will need to go for the third shot.
As soon as he goes down, switch to plasma boltblaster.
Then shoot into the canister forcing it to explore.
The true effect of the plasma state shows itself only once if it fades out, making him "Explore" dealing huge amounts of damage.
In the meantime, as he has two plasma canisters, its knockdown builds up once again. The tactic is the same as before, waiting for the opening recharge shoot.
Now again same as before, use the knockdown shot whenever possible third down should be enough to destroy him.
You have to speed up charging the knockdown shot shooting when possible dodging attacks.