AK47 and Phoenix 350L are the best weapons in the S+ tier; these are the most lethal weapons in Back 4 Blood. The most prominent weapons in the S tier are Scar and Uzi; you can equip them along with your primary weapons.
M4 Carbine and MP5 are the best weapons in tier A, while AA12 and M16 are the best weapons in the B tier. The most prominent weapons in tier C are Ranch Rifle and 870 Express, which are just average weapons. 357 Magnum and Beretta M9 (Auto) are the best weapons in tier D.
S+ Tier
| AK47 |
| Phoenix 350L |
S Tier
| Scar |
| Uzi |
| Glock 23 (Auto) |
| TEC 9 |
A Tier
| M4 Carbine |
| MP5 |
| Glock 23 |
| UMP45 |
| Vector |
| Super 90 |
| RPK |
| Desert Eagle |
| TAC14 |
| M249 |
B Tier
| AA12 |
| M16 |
| M1A |
| Barrett M95 (Burst) |
C Tier
| Ranch Rifle |
| 870 Express |
| Barrett M95 |
| The Belgian |
| Fire Axe |
| Hatchet |
D Tier
| 357 Magnum |
| Beretta M9 (Auto) |
| M1911 |
| Bat |
| Knife |
| Machete |